Natural vs Synthetic

In contrast to Naturally Desiccated Thyroid (NDT) containing T3 and T4, most synthetic medications contain T4 (or T3) only. Synthetic T4 maybe a satisfactory treatment for some patients with hypothyroidism. However, the numerous other patients who find relief of only some symptoms — or none at all — with synthetic T4 alone, there is an alternative.

The theory behind the use of synthetic T4 alone is that since the thyroid gland converts some T4 to T3, some of the synthetic T4 will be converted to T3 as well. One of the main concerns with this theory is that the thyroid gland of a hypothyroid person is already malfunctioning by not producing enough or any thyroid hormone, so its ability to convert T4 to T3 may be hampered too.

In reality, many patients don't start to feel normal again until they switch from synthetic to NDT (Thyroid USP). Natural Desiccated Thyroid hormone replacement has been used since the late 1800s, and it is one of the safest drugs available. It contains a full spectrum of thyroid hormones, T4 and T3 and also T2 and T1 as well (although the latter hormones aren't measured, but they aren't removed either).

The typical indication by the proponents of synthetic T4 is that NDT is unstable and inconsistent in its dosage. However, under the full USP monograph of both Thyroid USP as an ingredient and Thyroid USP Tablet as a finished product establishing full prescription status, this conventional argument could not be further from the truth. Unlike Nature-Throid™ and Westhroid™, synthetic medications have often been recalled due to batch inconsistencies. Yet most doctors are led to believe that desiccated thyroid is unstable.

To ensure that Nature-Throid™ and Westhroid™ Thyroid USP tablets are consistently potent from tablet to tablet and lot to lot, analytical tests are performed on the raw material (Thyroid USP powder) and on the actual tablets (finished product) to measure actual T4 and T3 activity.
 


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